Hypoxia and the carotid body.

Since the publication of the classical studies of Heymans et al (1930) it has been accepted that the carotid body is a chemoreceptor which monitors the oxygen tension of systemic arterial blood, and it has been extensively investigated by physiologists (Biscoe, 1971). Because chronic hypoxia is a major hazard of life at high altitude and of cardiorespiratory disease at sea level, it might be th...

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Appeasing the Carotid Body After Chronic Intermittent Hypoxia.

I recall vividly a conversation with the late Professor C. John Dickinson DM, FRCP, ARCO (Professor of Medicine and Chairman of the Department of Medicine at St. Bartholomew’s Hospital, London, 1975–1992) who remarked that in the majority of cases cardiovascular pathology occurred at night while asleep. John’s great hypothesis was that a shortage of oxygen to the brain because of high cerebrova...

متن کامل

Appeasing the Carotid Body After Chronic Intermittent Hypoxia

I recall vividly a conversation with the late Professor C. John Dickinson DM, FRCP, ARCO (Professor of Medicine and Chairman of the Department of Medicine at St. Bartholomew’s Hospital, London, 1975–1992) who remarked that in the majority of cases cardiovascular pathology occurred at night while asleep. John’s great hypothesis was that a shortage of oxygen to the brain because of high cerebrova...

متن کامل

Appeasing the Carotid Body After Chronic Intermittent Hypoxia

I recall vividly a conversation with the late Professor C. John Dickinson DM, FRCP, ARCO (Professor of Medicine and Chairman of the Department of Medicine at St. Bartholomew’s Hospital, London, 1975–1992) who remarked that in the majority of cases cardiovascular pathology occurred at night while asleep. John’s great hypothesis was that a shortage of oxygen to the brain because of high cerebrova...

متن کامل

Appeasing the Carotid Body After Chronic Intermittent Hypoxia

I recall vividly a conversation with the late Professor C. John Dickinson DM, FRCP, ARCO (Professor of Medicine and Chairman of the Department of Medicine at St. Bartholomew’s Hospital, London, 1975–1992) who remarked that in the majority of cases cardiovascular pathology occurred at night while asleep. John’s great hypothesis was that a shortage of oxygen to the brain because of high cerebrova...

متن کامل

Hypoxia and the carotid body.

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